What is PROSPER?
Every 40 seconds, someone in the U.S. has a stroke, with almost ¼ of these being recurrent strokes. The prognosis after stroke remains poor, with 1-year mortality rate of 15-30%. To date, many questions remain unanswered for real-world stroke survivors on what therapies will have the greatest impact on their well-being.
PROSPER is a national, sustainable model to improve decision-making and patient-centered stroke outcomes through comparative effectiveness research. Using Get With The Guidelines®-Stroke data linked with Medicare claims, we will evaluate outcomes prioritized by stroke survivor focus groups and surveys in 3 therapeutic areas:
PROSPER’s primary outcome for these 3 areas summarizes the “Home-time” (days alive and well outside of an institution) which is what patients believe are the most important factors to them:
Other selected outcomes to be evaluated include recurrent stroke, mortality and readmission. Patient-reported outcomes selected by our stakeholders include:
The knowledge gained from this work will inform the development of novel tools to empower stroke survivors to more effectively make treatment decisions regarding their stroke care.