Mission: Lifeline Data Request

Updated:Feb 3,2014

Mission: Lifeline®
is the American Heart Association's national initiative to advance systems of care for STEMI patients. The initiative seeks to reduce mortality and morbidity and improve the overall quality of care for STEMI patients.


Approved Database
In order to access and evaluate systems of care and their components, Mission: Lifeline recommends that STEMI systems and their components participate in a national data registry program. For hospitals and STEMI systems, ACTION Registry®-GWTG™ (AR-G) is the preferred data registry program. For those interested in studying and publishing data around STEMI Systems of Care and Mission: Lifeline, a data request form must be submitted.

In general, research questions being asked of ACTION Registry- GWTG that are related to STEMI Systems of Care will be under the purview of the Mission: Lifeline Science Task Force. STEMI System of Care topics include but are not limited to: pre-hospital, transfer and hospital analyses of STEMI patient populations. All other research queries for AR-G are under the purview of the AR-G Research and Publications Subcommittee.

 
Triage of Mission: Lifeline Related Queries
Any new proposal that comes through AR-G Research and Publications Process on STEMI only patients will be evaluated by the NCDR AR-G Steering Committee chairperson (s), NCDR AR-G Research and Publications Committee chairperson (s), and Mission: Lifeline Science Task Force chairperson(s) and for STEMI System of Care relevance.
  • If yes, then the proposal will be submitted through the Mission: Lifeline Publications Process.
  • If no, then the proposal will continue through the AR-G Publications Process.
 Any new proposal that comes through the Mission: Lifeline Science Task Force that is not STEMI System of Care related will be forwarded to the AR-G Research and Publications Subcommittee.
 
All existing AR-G publications in process (as of X date) will be managed as AR-G publications. An inventory of existing AR-G STEMI only publication will be provided to the Mission: Lifeline Science Task Force chairperson(s). Additionally, the Mission: Lifeline Science Task Force chairperson(s) or designee will have the option to review and comment on these existing AR-G STEMI only publications prior to submission for publication.
 
Overall Process Steps
 
1)      Download the Data Request Form and Guidelines.
2)      Submit completed Data Request Form to Manager, Quality Research Development via e-mail: laura.shuey@heart.org
3)      Submitted requests will be reviewed for feasibility, validity and novelty by Mission: Lifeline Science Task Force chairperson(s) and NCDR AR-G Research and Publications Committee chairperson (s). Feedback will be sent to the requesting investigator within 5 business days of submission.
4)      Approved requests are forwarded to Duke Clinical Research Institute (DCRI) for analysis and preparation of data
5)      Upon receipt of acceptance and prior to becoming active, first author and writing group members will be invited to a conference call on the research proposal with AHA staff, ML Science Task Force Chair, and/or designee and DCRI faculty and biostatistician.
6)      Completed analyses are sent from DCRI to primary investigator within agreed upon timeline of statistical assignment
7)      Draft manuscript/abstract is circulated to co-authors for review and sign-off
8)      Draft is reviewed separately by two AHA committees ((Mission: Lifeline Science Task Force (STF) and the Executive Database Steering Committee)) and by AR-G Research and Publications Subcommittee.  Each abstract review period is 1 week (5 business days) and each manuscript review period is two weeks (10 business days).
9)      Committee feedback and/or approval is sent to primary investigator within 7 days of abstract submission and 14 days of manuscript submission.
10) Final manuscript/abstract draft is submitted to journal/conference of choice by primary investigator or other designee
11) Conference acceptance, Journal decision, Online Release Date and Print Release Date are to be communicated back to the Manager, Quality Research Development by primary investigator or designee to ensure timely Mission: Lifeline marketing and promotion strategies.
 
Manuscript Requirements (that will aid authors in providing accurate language)
 
1)      Acknowledgement to include in Methods Section:
a)      ACTION Registry®–GWTG™ serves as the hospital data collection and evaluation mechanism for American Heart Association’ Mission: Lifeline. The Duke Clinical Research Institute (DCRI) serves as the data analysis center and has an agreement to analyze the aggregate de-identified data for research purposes.
 
Informational, not required: Hospitals participating in the registry submit clinical information regarding the medical history, hospital care, and outcomes of consecutive patients hospitalized for acute coronary syndrome using an online, interactive case report form supplied by ACTION Registry®–GWTG™.
 
b) Any STEMI Systems, hospital and EMS information that was not completed in ACTION Registry®–GWTG™ could be supplied through the AHA online survey tools, Vovici Corporation (Dulles, Virginia) or ROK Technologies (Charleston, South Carolina).   
 
2) Research Disclosure
All participating institutions were required to comply with local regulatory and privacy guidelines and, if required, to secure institutional review board approval. Because data were used primarily at the local site for quality improvement, sites were granted a waiver of informed consent under the common rule.
 
ACTION Registry®–GWTG™ served as the registry coordinating center. Vovici and ROK served as the Mission: Lifeline data collection tools. The Duke Clinical Research Institute (Durham, North Carolina) served as the data analysis center and institutional review board approval was granted to analyze aggregate de-identified data for research purposes.
 
For additional guidelines around single center and regional abstracts and guidelines, please refer to the publication policy.
 
Points of Contact
If you have any questions regarding the publication process for Mission: Lifeline publications in general, please visit contact Paula.Feather@heart.org or Laura.Shuey@heart.org.

If you have any questions regarding the publication process for AR-G publications in general, please contact NCDR.